iindaba

I-splanchnic inversion (kubandakanya i-splanchnic inversion epheleleyo [i-dextrocardia] kunye ne-partial splanchnic inversion [levocardia]) yinto engaqhelekanga yokuphuhliswa kokuzalwa apho isalathiso se-splanchnic kwizigulane sichasene nabantu abaqhelekileyo. Siye sabona ukonyuka okubonakalayo kwenani leemeko ze-fetal visceral inversion eziqinisekiswe yi-ultrasound kwisibhedlele sethu kwiinyanga ezimbalwa emva kokurhoxiswa komgaqo-nkqubo "wokukhutshwa kwe-zero" we-COVID-19 e-China.

Ngokuphonononga idatha yeklinikhi evela kumaziko amabini okubelekisa kwimimandla eyahlukeneyo yaseChina, sinqume ukuba kwenzeka ntoni kwi-fetal visceral inversion ukususela ngoJanuwari 2014 ukuya kuJulayi 2023. Kwiinyanga ezisixhenxe zokuqala ze-2023, iziganeko ze-inversion yangaphakathi (i-ultrasonography yesiqhelo yangaphambi kokubeletha kunye nokuxilongwa malunga ne-20 ukuya kwi-24 ye-protocol ye-diagnostic ngaphandle kwe-protocol yokuguqulwa kwe-gesta okanye i-protocol) amaxesha aphezulu kunomyinge wezehlo zonyaka ze-2014-2022 kuwo omabini amaziko (Umfanekiso 1).

Iziganeko ze-visceral inversion zanyuka ngo-Ephreli 2023 kwaye zahlala ziphakamileyo kwaze kwaba nguJuni 2023. Ukususela ngoJanuwari 2023 ukuya kuJulayi 2023, iimeko ze-56 ze-splanchnosis zifunyenwe (i-52 iyonke i-splanchnosis kunye ne-4 inxenye ye-splanchnosis). Inani losulelo lwe-SARS-CoV-2 liye landa emva kokucinywa komgaqo-nkqubo we-COVID-19 “wosulelo lweziro”, okulandelwa kukwanda kwamatyala e-visceral inversion. Kuqikelelwa ukuba uqhaqho losulelo lwe-SARS-CoV-2 lwaqala ekuqaleni kukaDisemba ka-2022, lwanyuka nge-20 kaDisemba 2022, kwaye lwaphela ekuqaleni kukaFebruwari ka-2023, ekugqibeleni lwachaphazela malunga ne-82% yabemi base China. Ngelixa kungekho zigqibo zinokuthathwa malunga ne-causality, uqwalaselo lwethu lucebisa unxulumano olunokubakho phakathi kosulelo lwe-SARS-CoV-2 kunye nokuguqulwa kwe-fetus visceral, eqinisekisa ngakumbi.funda.

Umzobo A ubonisa izehlo eziqinisekisiweyo ze-fetus splanchnic inversion kumaziko amabini okubelekisa ukususela ngoJanuwari 2014 ukuya kuJulayi 2023. Amanani aphezulu kwibhari yebhantshi abonisa inani elipheleleyo leemeko zonyaka ngamnye. Iziganeko zabikwa njengenani leemeko ngabasetyhini abakhulelweyo abayi-10,000 abaye bafumana ukuhlolwa kwe-ultrasound. Umzobo B ubonisa inani leemeko eziqinisekisiweyo ze-visceral inversion ukususela ngoJanuwari 2023 ukuya kuJulayi 2023 kwi-China Welfare Society International Peace Maternal and Child Health Hospital (IPMCH) e-Shanghai kunye neSibhedlele seSibhedlele sePhondo saseHunan kunye nomntwana (HPM) e-Changsha.

Ukuguqulwa kwe-visceral ye-Congenital inversion inxulunyaniswa nokuhanjiswa kwehomoni ye-morphogenetic engaqhelekanga kunye nokungasebenzi kakuhle komququzeleli we-cilium kwinqanaba lokuqala lokumitha kwe-embryo ekhohlo ukuya ngasekunene kwe-asymmetry. Nangona usulelo oluthe nkqo lwe-SARS-CoV-2 lusenempikiswano, usulelo lwe-embryo ekukhulelweni kwangoko lunokuchaphazela ukukhula kwe-fetus visceral asymmetrical. Ukongeza, i-SARS-CoV-2 inokuchaphazela ngokungathanga ngqo ukusebenza kweziko lasekhohlo ngasekunene ngempendulo yalo yokukrala kamama, ngaloo ndlela ithintele uphuhliso lwe-visceral asymmetrical. Kwizifundo ezizayo, uhlalutyo olongezelelweyo luyimfuneko ukuze kuqinisekiswe ukuba ukungahambi kakuhle kwemfuza okuhambelana ne-primary ciliary dyskinesia enokuthi ingabonakali kwi-prenatal genetic screening ayinaxanduva kwezi meko, kunye nokuvavanya indima enokubakho yezinto ezisingqongileyo ekwandeni kwe-visceral inpositions. Kufuneka kuqatshelwe ukuba nangona izehlo ze-visceral inversion zonyuka kumaziko amabini okubelekisa emva kosulelo lwe-SARS-CoV-2, imeko yeklinikhi yokuguqulwa kwe-visceral isanqabile kakhulu.